Salmonella Acquires Lysosome-associated Membrane Protein 1 (LAMP1) on Phagosomes from Golgi via SipC Protein-mediated Recruitment of Host Syntaxin6*

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DC Field	Value	Language
dc.contributor.author	Mukhopadhyay, Amitabha	-
dc.date.accessioned	2014-12-17T07:47:12Z	-
dc.date.available	2014-12-17T07:47:12Z	-
dc.date.issued	2011	-
dc.identifier.uri	http://hdl.handle.net/123456789/435	-
dc.description.abstract	Background: Intracellular pathogens avoid lysosomal targeting but recruit lysosome-associated membrane protein 1 (LAMP1), the mechanism of which remains unclear. Results: SipC binds with Syntaxin6 and acquires LAMP1 on the phagosome by fusing with Golgi-derived vesicles. Conclusion: This is a novel mechanism by which Salmonella acquires LAMP1 from Golgi. Significance: This is the first demonstration showing how an intracellular pathogen like Salmonella recruits LAMP1 without fusing with lysosomes	en_US
dc.publisher	American Society for Biochemistry and Molecular Biology	en_US
dc.title	Salmonella Acquires Lysosome-associated Membrane Protein 1 (LAMP1) on Phagosomes from Golgi via SipC Protein-mediated Recruitment of Host Syntaxin6*	en_US
dc.contributor.coauthor	Parashuraman, Seetharaman	-
dc.contributor.coauthor	Rastogi, Ruchir	-
dc.contributor.coauthor	Madan, Richa	-
dc.keyword	lysosome-associated membrane protein 1	en_US
dc.journal	THE JOURNAL OF BIOLOGICAL CHEMISTRY	en_US
dc.volumeno	287	en_US
dc.issueno	8	en_US
dc.pages	5574-5587	en_US
Appears in Collections:	Cell Biology- I, Publications

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